Bremelanotide PT-141 by Subcutaneous Injection

[Semin]

Melanocortin Peptide PT-141 Injections

Bremelanotide PT-141 is a generic term for a new medication which has shown promise in effectively treating sexual dysfunction in men (erectile dysfunction or impotence) as well as sexual dysfunction in women (sexual arousal disorder). It was developed from Melanotan 2 (MT-II), which is researched as a sunless tanning agent. PT-141 is a metabolite of MT-II that lacks the C-terminal amide function-stripping away much of tanning effect.



Bremelanotide works through a mechanism of action involving the central nervous system rather than directly on the vascular system.

Bremelanotide has the amino acid sequence Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH or cyclo-[Nle4, Asp5, D-Phe7, Lys10]alpha-MSH-(4-10). It is a cyclic hepta-peptide lactam analog of alpha-melanocyte-stimulating hormone (alpha-MSH) that activates the melanocortin receptors MC3-R and MC4-R in the central nervous system. Molecular formula being C50H68N14O10 and a molecular weight of 1025.2.



Mixing PT-141

Combine10MG PT-141 freeze dried powder with 1mL/100units of bacteriostatic or sterile water, yielding a solution of 1mg PT-141 for every 10units of liquid. Make every effort to maintain a sterile environment while mixing the product.

Pre-load Bremelanotide PT141 Dosages

To make this easier, get some insulin syringes - they are usually measured in generic "units". 100 units = 1mL. Recommended Needle]
Recommended PT-141 Storage

Now freeze the filled syringes that are not being injected immediately. Do not freeze the mixed PT-141 without prefilling the syringes - you degrade the quality of the peptide every time you unfreeze it.

For the rest of the PT-141, do not add mixing water until you are ready to use it. Store the undiluted product in the freezer until you mix in the water, then prefill again and freeze as described above.

When Should I Dose PT-141?

Most find great results if administered hours before you desire the product to take effect. PT-141, injected, has a unique window of opportunity lasting 6-72 hours after bremelanotide peptide subq injection.

[Semin]

PT141 (aka Bremelanotide) is a generic term for a new pharmaceutical grade synthetic aphrodisiac currently available, which has been developed to address Erectile / Sexual Dysfunction or impotence in men, as well as sexual dysfunction in women (sexual arousal disorder).

PT-141 directly targets the brain’s arousal center and doesn’t just work with the vascular system to increase blood flow to the genital area, it has the potential to treat women with sexual dysfunction problems, especially those with lack of sexual desire.

Bremelanotide is a melanocortin peptide hormone.* PT-141 binds to the melanocortin 4 receptor (MC4R) in particular in the brain.* Nine out of ten volunteers experienced sexual arousal in trials.*

Bremelanotide (PT-141) was originally developed from the peptide known as Melanotan 2 (MT-II).* PT-141 is a metabolite of MT-II that lacks the C-terminal amide function-stripping away tanning properties. Whilst being tested as a sunless tanning agent , during the clinical trials, it stimulated tanning, but it also had an interesting side effect, sexual arousal and spontaneous erections. This led to it being studied in new clinical studies as a way to alleviate male sexual and Erectile / Sexual Dysfunction, as well as enhance female sexual function.

PT-141 directly targets the brain’s arousal center and doesn’t just work with the vascular system to increase blood flow to the genital area, it has the potential to treat women with sexual dysfunction problems, especially those with lack of sexual desire.

For women, PT-141 works twofold in that it increases sexual arousal and function. For men it is primarily is used for Erectile Dysfunction (ED), but for women it has been shown to increase the desire for sex and well as the enjoyment of sex.

Women who have taken part in trials said that they felt a "tingling and a throbbing" along with "a strong desire to have sex."* An initial flush occurs post injection, followed by nausea which is dose dependent.* For most, effects generally do not take place until a couple hours post injection, peaking around the four hour mark.* * Men said PT-141 made them feel "younger and more energetic" as well as sexually interested and aroused. "You're ready to take your pants off and go," said one user "a drug that makes you not only able to but eager to."

PT-141 is the only synthetic aphrodisiac.* Studies have shown Bremelanotide to be effective in treating sexual dysfunction in both men (erectile dysfunction or impotence) and women (sexual arousal disorder).* Unlike Viagra and other related medications (PDE5s), PT-141 does not act upon the vascular system, but directly through the nervous system (hypothalamus) to increase desire.* Viagra, Cials and Levitra are not considered aphrodisiacs as they do not have any direct effect on the libido.* However, treatment with PDE5 inhibitors and PT-141 are known to have a synergistic effect.

Bremelanotide comes in 10mg and 2mg vial sizes.* Freeze dried Melanotan peptides (PT-141) are very durable and stable.* The PT-141 peptide reconstituted with bacteriostatic water remains potent in the fridge for months.

PT 141 injection (subcutaneous), has a unique window of opportunity lasting six to 72 hours.* In lab trials female rats exposed to PT-141 began "flirting" with male rats for sex. Postures and movements left no doubt in the male rats minds that they were in the mood.* The human PT-141 date is one where the dosage precedes the activity by at least a couple hours.* When the stars align, hours after the injection, ...this is your window of opportunity, enjoy.

[quasenunca]

I am trying to determine whether it is better to freeze the unmixed product or not and am a bit confused. The above advice states "Do not freeze the mixed PT-141 without prefilling the syringes - you degrade the quality of the peptide every time you unfreeze it.

For the rest of the PT-141, do not add mixing water until you are ready to use it. Store the undiluted product in the freezer until you mix in the water, then prefill again and freeze as described above."

If the peptide is degraded by unfreezing, then why freeze the undiluted product since you will have to unfreeze it before mixing? Thanks in advance for any clarification.

[Semin]

"
I am trying to determine whether it is better to freeze the unmixed product or not and am a bit confused.
"

It is not a big deal either way. Leave the freezer out of the equation altogether, you will be just fine.* PT-141 is durable and preserves for a long time in bacteriostatic water inside the fridge.*

[bjones]

Chris , do you get the same effects from MT II as the PT ? I would ike to get the tan too but was wondering if one was more potent on the libido than the other
Thanks

[Semin]

"
Chris , do you get the same effects from MT II as the PT ? I would ike to get the tan too but was wondering if one was more potent on the libido than the other
Thanks
"

Yes sir, the aphrodisiac effect of MT-II = PT-141

[normaltype]

How long will it last mixed with bac water and stored at room temp?

[peptideguru]

"
How long will it last mixed with bac water and stored at room temp?
"

2-3 months

[Courtney]

It is not a big deal either way. Leave the freezer out of the equation altogether, you will be just fine.* PT-141 is durable and preserves for a long time in bacteriostatic water inside the fridge.*

I have read that the bac water should be discarded, as well as the pt-141 after one month because it is no longer good. Also, have read pt-141 degrades in the fridge at some point. I have had mine for 32 days in the fridge and was just about to throw it out and I have only tested it 3 times with a very small amount. Thoughts?

[Courtney]

Also, should this be injected shallow or deeper into the belly fat. I have both : )