I was wondering if any long term users could share some of their experiences with me.. I used mt2 for 3 summers but I'm really starting to think about the long term effects..
A woman I work with knew a woman who developed a tumor at her injecting site. The lady sadly passed away. Doctors could not confirm it was the mt2.
Has anyone had any scares? Moles removed?
My Dad passed away 10 months ago from melanoma in his bowel. He never used sunbeds... The sensible part of me says don't do it and that I'm being an idiot even considering it again after what happened with my dad. The side that wants to be brown says this can happen to you even when you avoid all the things in life that they say increase your chances...
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I was wondering if any long term users could share some of their experiences with me.. I used mt2 for 3 summers but I'm really starting to think about the long term effects..
A woman I work with knew a woman who developed a tumor at her injecting site. The lady sadly passed away. Doctors could not confirm it was the mt2.
Has anyone had any scares? Moles removed?
My Dad passed away 10 months ago from melanoma in his bowel. He never used sunbeds... The sensible part of me says don't do it and that I'm being an idiot even considering it again after what happened with my dad. The side that wants to be brown says this can happen to you even when you avoid all the things in life that they say increase your chances...
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a tumor at her INJECTION SITE??* ]
sorry about your father.. all i can say is yes melanoma can appear in places where there has been no sun exposure. it's important to keep your vitamin d levels high as that is responsible for regulating cell proliferation and apoptosis. low vitamin d has been linked to many cancers including melanoma.
unfortunately I cannot offer any other comfort because I too am conflicted as I'm sure many users are. for most here the tan for them has been life-changing. there is an old saying "if you want to dance you have to pay the fiddle." meaning you have to take the good with the bad. although there has never been any concrete evidence showing that melanoma or other skin cancers are linked with melanotan and even an official statement from Palatin, the circumstances are still strange... despite prior sunbed usage, most of the people documentated as having melanoma's excised after doing melanotan are only in their early 20's....
I honestly couldn't tell you. It's actually her man that works with the the lady who's passed away's husband. She used to use mt2 too but now won't go near it because of it.
I didn't know that about the vitamin d thanks. I wonder what's worse... The mt2 or the actual sunbeds?!
You read articles on it and think if healthcare professionals are so concerned with the amount of users why don't they just get all the relevant testing done.
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unfortunately I cannot offer any other comfort because I too am conflicted as I'm sure many users are. for most here the tan for them has been life-changing. there is an old saying "if you want to dance you have to pay the fiddle." meaning you have to take the good with the bad. although there has never been any concrete evidence showing that melanoma or other skin cancers are linked with melanotan and even an official statement from Palatin, the circumstances are still strange... despite prior sunbed usage, most of the people documentated as having melanoma's excised after doing melanotan are only in their early 20's....
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If you are scared about melanoma in particular, then skip on the tanning beds. In your twenties, women are much more likely to get melanoma in men and a big reason for this is tanning bed use. Men are way more likely to get melanoma during old age though, probably related to increased cumulative sun exposure and taking less care of their skin. This definitely accounts for a large part of this, although physiological differences could account for some too. http://www.skincancer.org/media/legacy/stories/melanoma_letter/ML_28_1_Figure1_graph.jpg
I am just as concerned as you. I have used MT2 for 1 year with 500mcg every day. The brown skincolor has revealed a lot of growths in the skin that I had before I took MT2, and this is a good thing. I have removed almost all by cutting it away or by using a razor blade, apple acid or hydrogen peroxide. Moles, freckles, scars, warts, precaners, and so - I have removed them all myself, and my skin looks much better and are smooth now. My skin was unhealthy, dry and ugly before I used MT2.
I have several family members who have died of cancer and melanoma. The person who died of melanoma was always pale and sunbathed never, causing me to continue with MT2, because there are claims that it is precisely protects against melanoma and Actinic Keratosis.
I am also concerned about the extent to which MT2 affects blood chemistry, heart rhythm and eyes.
"causing me to continue with MT2, because there are claims that it is precisely protects against melanoma [...]
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To be precise, the claims are that (eu)melanin protects against sundamage, which may result in skin cancer.
The claim is not and never has been, that the Melanotans protect against skin cancer.
"causing me to continue with MT2, because there are claims that it is precisely protects against melanoma [...]
"
To be precise, the claims are that (eu)melanin protects against sundamage, which may result in skin cancer.
The claim is not and never has been, that the Melanotans protect against skin cancer.
"
Hey Jacques, where have you been? Are you able to get in touch with Scott at all? I've tracked down some of the old mods of that board that don't post here but no one seems to know where he's gone to?* ]
As far as MT2 or 1 being directly protective... the general stance long ago was that it was that only the tan that was produced was the protective factor and Melanotan held no protective properties on it's own. I've been reading much new information lately provides new insight.
It appears that pheomelanin (red pigment) produces reactive oxygen species that damages DNA in the melanocytes and induces carcinogenesis even without ANY sun exposure. This is why redheads are at the greatest risk of melanoma and skin cancers without having barely any sun exposure throughout their lifetime. Even moreso than albinos without any pigment.
Now what drug can decrease pheomelanin and switch the signalling pathways to instead produce the beneficial eumelanin? Besides eumelanin's effect on preventing UV damage it's also showing it's ability to chemically ‘cage’ pheomelanin, neutralizing its oxidation-damaging effect. Look at these.
Of course UV damage is just as harmful as ever, but new data suggests melanotan MIGHT have some other protective effects besides tanning. Endymoin's opinion is that a tan is merely just a side effect of Scenesse's ability and not it's actual direct purpose... atleast the direction Clinuvel is going.
"causing me to continue with MT2, because there are claims that it is precisely protects against melanoma [...]
"
To be precise, the claims are that (eu)melanin protects against sundamage, which may result in skin cancer.
The claim is not and never has been, that the Melanotans protect against skin cancer.
"
While it need to be researched more, one of the top researchers of alpha-msh and the MC1R receptor has published some papers saying it does]
"One skin cancer prevention strategy that we are developing is based on synthesizing and testing melanocortin analogs that reduce and repair DNA damage resulting from exposure to solar ultraviolet (UV) radiation, in addition to stimulating pigmentation. Previously, we reported the effects of tetrapeptide analogs of alpha-melanocortin (alpha-MSH) that were more potent and stable than the physiological alpha-MSH, and mimicked its photoprotective effects against UV-induced DNA damage in human melanocytes. Here, we report on a panel of tripeptide analogs consisting of a modified alpha-MSH core His(6)-d-Phe(7)-Arg(8), which contained different N-capping groups, C-terminal modifications, or arginine mimics. The most potent tripeptides in activating cAMP formation and tyrosinase of human melanocytes were three analogs with C-terminal modifications. The most effective C-terminal tripeptide mimicked alpha-MSH in reducing hydrogen peroxide generation and enhancing nucleotide excision repair following UV irradiation. The effects of these three analogs required functional MC1R, as they were absent in human melanocytes that expressed non-functional receptor. These results demonstrate activation of the MC1R by tripeptide melanocortin analogs. Designing small analogs for topical delivery should prove practical and efficacious for skin cancer prevention."
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