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Objective

Melanocortin-4 receptors (MC4Rs) are highly expressed by dopamine-secreting neurons of the mesolimbic tract, but their functional role has not been fully resolved. Voluntary wheel...

Introduction

Intra-abdominal hypertension is a life-threatening disease. Melanocortin-4 (MC4) receptor activation exhibits life-saving properties. The aim of the present study was to examine...

Source:

http://www.nature.com/jid/journal/v135/n10/abs/jid2015197a.html

Definition of terms

What is Hypertrophic Scarring or HTS? Hypertrophic scarring (HTS) is a fibroproliferative...

Significance of the Study

To know if melanocortin receptors are present in the human endometrium and what are its significance in it.

Results

MCR1-5 are expressed in endometrium to varying...

Significance of the study

The natural tendency for weight gain is damaging to human health. But under certain environmental conditions wherein nutrients are limited, this trait can be highly...

Wow, this is such great news for a lot of patients suffering from Gout! My uncle is one of them and he always complains of pain in his knees, ankles and toes. His treatment will last for about six...

MSH has therefore a role in massive skin injuries, like burns or wounds. Repair from these types of skin injuries can take a while. My CS incision is still very visible and red and it's been a year...

Cardiovascular disorders are very common nowadays. It's still confusing to people, to me, what really triggers these diseases. Some say it's the bad cholesterol in food, some say that it has nothing...

Autism patients vary from highly functioning individuals to low functioning individuals. This means that they can live their lives fully functioning independently or not as well as others. They also...

Melanotan has been known to be of help in obesity and body weight problems. But these findings about the melanocortin accessory proteins also have significant value since they are directly involved...

I am one of those people who can sometimes, not control food consumption and hence body weight. And there are a lot of people struggling with obesity nowadays. Melanotan II can be quite a good...

Solar urticaria is a rare condition in which exposure to UV light, sometimes even visible light, leads to hives in that certain person with the condition. The trials for using Melanotan for urticaria...

It's good to know that Melanotan has a role in people with damaged MC1R receptors. Response to damage such as UV radiation is an important indication of how a person's repair system works. If a...

This can be an alternative for people who don't respond well to Melanotropin. Though again, the D-Phe-containing hexapeptide is more potent and active, the dose will probably have to be lesser than...

I think this study is such a great one for traumatic injury patients. I hope many more studies will delve into this topic and certainly prove that administration of tripeptide is indeed helpful in...

I think that the survival of the fittest is apt for this scenario. Neanderthals have this certain mutation in their MC1R gene and they did not survive. They were not able to adjust to the environment...

Wow! What exciting news! I am one of those people who always dread going to the dentist. But this discovery can sure make trips to the dentist more fun. Of course, nothing beats brushing and flossing...

Hi! They say that if your MT is legit, you will experience side effects. Within minutes of injecting it, you will feel flushed or slightly nauseous. If you do feel these things, then what you got is...

Hi! Thanks for updating us! Good to know that it's not the Melanotan that is causing them. I get these red spots sometimes too but more when it's warm and hot. It can also be because of your workout,...

I generally have quite a few moles which makes me reluctant to try Melanotan. As I've read lots of experiences by other people that it does add more freckles or moles. Or can even darken existing...

Melanocortins are known to decrease body weight. But its implications in obesity are not yet explored. I think such patients suffering from obesity can benefit from taking melanocortins. With proper...

I think Melanotan 2 has been studied about this subject matter previously. And it has been proven to help males with ED problems. But it's best to follow the following guidelines before using it:
...

This could be a new way of preventing Alzheimer's disease especially in at risk individuals. Alzheimer's has wreaked havoc on many families including mine. My grandmother is stricken by it and she...

This is something that really confuses me. So when is the appropriate time for sun exposure really? I try to expose my son to the sun from 6 AM to 9 PM. Is that okay? One doctor from television went...

Vitiligo is the loss of skin color that causes blotches or patches in patients. It occurs when the cells that produce melanin die. So I think melanotan has a place for treatment in this condition. As...