For example, if you currently have THC in your bloodstream will it blunt the release of GH from a GHRP/GHRF dose?
For example, if you currently have THC in your bloodstream will it blunt the release of GH from a GHRP/GHRF dose?
It stimulates somatostatin release. And yes it will blunt GH release.Originally Posted by Jim
Ha! Interesting. I had no idea. Well I havent smoked in years anyway.
If you want to build max muscle, don't smoke it "chronically"
THC lowers gh:
In vitro effect of delta 9-tetrahydrocannabinol to stimulate somatostatin release and block that of luteinizing hormone-releasing hormone by suppression of the release of prostaglandin E2
THC lowers test:
Endocrine effects of marijuana in the male: preclinical studies. - PubMed - NCBI
I always thought that since increases your dope-amine levels in the brain that it could potentially have a slight stimulatory effect. At any rate its much better for pain management than nsaids or other harsher narco pain relievers that's for sure..
So as a chronic smoker am I wasting my time on peptides? Is there a dosage schedule that would be better suited? Something I should supplement with pre injection like arganine?
Lately I've been partaking more frequently, but I'm always clear in the morning. Worst case scenario you could always dose in the morning with peptides, and 5 hours later smoke up. I'm not an expert but this could work. Depends on how long the blunting effects last. I know THC stays in the system for a long time, but I would be surprised to learn that it blunts GH release for longer than a few hours.
Because of the nature of THC's effects on users and its GH blunting properties, using both substances isn't conducive to great results, but with careful planning I BELIEVE it's possible to obtain a positive effect from both.
Theoretically it would make any GH released or introduced ineffective to the degree it stimulates somatostatin. But I can't say for sure.
You have to decide whether THC or GH is your highest priority.
Here is a pretty good little paper on it:
http://www.ukcia.org/research/EndocrineEffects.pdf
I've taken many shots of peptides completely baked, especially pre-bed shots and the effects are certainly still there. Increase in carpal tunnel pain shortly after injection, increased water retention, etc.
Are you using any AAS?
No doubt that marijuana use is not optimal for anything health oriented.
Having said that, I can say that unfortunately I smoke weed sometime. The addition of Mod GRF + Ipamorelin to my weed smoking has done wonders for me - in terms of all things "GH".
Would I be even better without the weed? Probably
Last edited by Porzingis; 28th December 2015 at 01:22 AM.
Pot definitely brought me down. I've leaned out a lot since quitting.
I also would develop bronchitis about every three months or so like clockwork for about 4 years. I havent had a case since quitting a couple of years back.
Will somatostatin release from THC simply prevent any further release in GH? Or would it lead to an immediate reduction in GH levels?
One thing I notice is I look softer for 24-48 hrs after I vaporize... no change in calories in or out, but I notice it everytime.
So is there a way to make a window to keep somatostain down during your peptide and gh pulse with thc in your system? for example taking a choline supplement during the day.
Why not just quit smoking?
Apparently MJ improves insulin sensitivity and waist line circumference. Maybe the green is not so bad after all.
http://www.amjmed.com/article/S0002-...200-3/abstract
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