As a potential user of HCG, it is of utmost importance to arm you with the proper knowledge of the product, prior to purchase and usage. By doing so, you will learn all about the product, from the basics, to the most vital of information about it. Everything you need to know will also help you in achieving the best results possible.
HCG basically stands for the Human Chorionic Gonadotropin, which is usually extracted from the urine of conceiving women. It is not considered as a schedule medication, but is similar to the Liquidex and Clomid, as far as the United States laws are concerned. A prescription is required in purchasing such product in the market. Hence, it is a legal drug.

Purpose of HCG

HCG is used in helping women to get pregnant, although it is also used in stimulating the production of testosterone in males. HCG mimics the Leutenizing Hormone (LH), causing the Leydig cells in the gonads to testosterone production. The effect equates to the restoration of the testes’ size in a rapid pace.
HCG is widely used by bodybuilders who are going through a very heavy or long cycles, especially when the Hypothalamic-Pituitary-Testicular Axis (HPTA) is severely suppressed. The use and benefits of HCG are mostly distinct on heavy and/or long cycles.

Administration of HCG
HCG is commonly administered through intramuscular or Sub-q injection, and is not exclusive for Post Cycle Therapy (PCT). In fact, it should not be used only for PCT because Nolva or Clomid could be a better plan. While HCG mimics LH, the human body will not be producing its own LH. Once HCG stops, the testes stop making test until the body begins producing its own, adequate levels of LH. This process usually takes a long period without the use of supplements such as the Nolvadex or Clomid in stimulating LH production. Hence, these should be continued for at least two weeks, after discontinuing the use of HCG so as to avoid problems.

HCG Cycle
HCG provides the best results by using it during the last three or four weeks of a steroid cycle. Avoid the use when there are signs of gyno as the product could make it worse. For every cycle or PCT, at least 10,000 IU’s of HCG are necessary. But, with a properly-planned PCT, perhaps only 5,000 IU’s of HCG would do well. During the last four weeks of a cycle, an anti-estrogen is necessary to use along with the product.

HCG Dosage
Based on recommendations, the best dose for HCG is at 500 IU up to 1,000 IU, while more than the recommended dosage could result in excessive aromatization. However, other people might not respond to less that 500 IU of HCG. Therefore, shooting 500 IU’s of HCG two times per week, or 1,000 IU’s once a week during the last four weeks of a cycle will do very well.

Boosting Testosterone
HCG can boost the testosterone production above the baseline without using steroids. However, this is not highly recommended. A continuous use of HCG will desensitize the Leydig cells into LH, which means that stopping the HCG use as a synthetic LH will result in nothing. Nolvadex or Clomid could help in the restoration of natural LH production, but, a discontinued use of HCG does not lead to an effective natural LH production as it was before. Nolvadex, Clomid or Anasrtrozole could be the best choices in boosting the natural testosterone production.
Meanwhile, HCG can boost the testosterone for up to five days, following the final dose. However, the half-life of the drug could be very short and might not be active at that point in time.

HCG Causes Gyno
HCG can cause gyno as estrogen is elevated by two distinct ways through the use of HCG. Testosterone could rise sharply, allowing more testosterone in aromatizing the estrogen. Moreover, HCG could result in a small amount of estrogen production, but is not as a result of the aromatizing process. To counteract this result, the use of anti-aromatizing agents, such as Letrozole, Arimidex, or Liquidex, combined with HCG is ideal. An estrogen receptor blocker like Nolvadex is also common in combating the aromatizing process. Furthermore, Nolvadex offers additional benefits in preventing a negative, estrogen feedback to the HPTA throughout an HCG therapy. Otherwise, the therapy’s efficiency may be lessened slightly.

Proper Preparation and Usage
The typical packaging of HCG comes in two vials, one with the powdered HCG, while the other has the solvent or diluent in it. The general diluent is bacteriostatic water or the sterile water with .09% sodium chloride. Regardless the brand and version of HCG, the package comes with adequate diluents to make concentrations between 250 and 10,000 IU per milliliter (ml).
In order to arrive at a 5,000 IU per ml, add 1ml diluents to 5,000 IU of HCG, while adding 5ml diluents would result in 1,000 IU per ml. A 10ml of diluents would result in 500 IU per ml. It is a simple mathematics and is the proper dosing procedure.
At times, the package does not include adequate diluents in making a desired concentration. In this case, you have two options in making the entire thing easy and measuring the proper dosage.
1. Purchase a U-100 type of insulin syringes. The 100IU is equivalent to 1ml, talking about the graduated markings. However, it does not mean that you have to fill up until the 100 mark, hence, you are making and taking 100IU of HCG. Keep in mind that ‘IU’ does not measure weight or volume, but to measure the effectiveness of a drug or compound for a desired response. Also, all compounds are different. While the insulin syringes are made specifically for insulin, and not HCG, the level of concentration entirely varies. Therefore, making and taking a 500IU of HCG shot is achieved by injecting 10IU of diluent in the syringe scale to the 5,000 IU per ml of HCG.
2. Secondly, you can buy bacteriostatic water on the internet, as where it is easily found. This will make concentrations more accurate with the use of regular syringe. Mix the substances together, noticing easy dissolution. But, take extra care in reconstituting the product as HCG could be very unstable, preventing too much shaking or creating a foamy consistency. Just be gentle in running the bacteriostatic water down the side of the vial, while keeping everything sterile at the same time. Unused or leftover HCG can be refrigerated and could last for up to 30 days, even after reconstitution.

Absorption and Elimination of HCG
A rise in HCG level is detected in two hours, while its peak is reached in six hours. The level tends to remain for 36 hours. However, the level begins to drop at 48 hours, approaching the baseline at 72 hours.

10-Week HCG Supply Model
As one of the peptides, HCG is also made of a large and complex molecular structure, bound by very weak carbon bonds at some point in its structure. Hence, it is sensitive to light, heat, freezing, and shock. Nonetheless, it is imperative to handle the delicate product from the purchase, to the preparation, reconstitution, and so on.
Before moving on to the 10-week HCG supply model, it is crucial to keep everything and your environment as sterile as possible. Make use of lab gloves if you can. It is now time to start with the procedures:
1. Buy an empty 10ml vial and 30ml of bacteriostatic water.
2. Crack-top each vial in the HCG supply kit.
3. Grab a slin pin, drawing up 1ml of bacteriostatic water.
4. Run 1ml of water down the side of the cracked-top vial that contains the lypholized HCG powder.
5. Let it mix on its own.
6. Add 9ml of water to the stoppered empty vial with IM pin (3x3ml).
7. Draw up the 1ml solution slowly.
8. Next is to insert the loaded slin pin into the 10ml vial that contains bacteriostatic water.
9. Invert the 10ml vial, just enough in submerging the needle, and then push the plunger slowly.
10.In the same manner, pull the plunger back out, pushing in again to rinse.
11. It is now time to withdraw the slin pin and then discard the material.
12. Refrigerate the final product.
Now, you have a 10ml HCG dosed at 500 IU per ml. Through assumption, you can use 250 IU twice a week. Hence, the entire procedure is a 10-week supply.

Warnings and Guidelines
Before any usage of the product, it is also important to read and understand the sticky titled injection guide. There would be a huge exception as HCG is injected sub-cutaneously or sub-q, which means under the skin with a u-100 insulin needle. HCG is shock-sensitive, hence, gentle and slow movements are required.
Once you have drawn up the specific or desired dose, it is now time to set the pin down through the needle hanging over the edge of whatever surface that you’re using. Carefully find a spot on your abdomen or legs, which you can reach with both of your hands, pinching up at least half inch of skin. The potential injection site should be swabbed with alcohol.
For instance, the right side of the navel is the desired injection spot, pinching an inch of the skin. As you pinch it with your left hand, re-swab the site with the right hand or fingers. Pick the pin up and stick it in the skin, pushing the plunger, withdrawing it, and then discarding it properly.

Calculating and Mixing HCG
Essentially, there is no specific ratio of cc/ml into IU, but it would depend on how you will mix it. It will be simple, just by diluting 5,000 IU HCG with 5ml or 5cc of solvent, which will result in 1,000 Iu per ml or cc. Divide the 5,000 with 10ml, resulting in 500 IU per ml. Therefore, it would entirely depend on the HCG concentration per ampoule or vial.
Certainly, there are essential things to start mixing HCG, including bacteriostatic water and empty vials of 5ml.
1. First, open the HCG ampoule containing the HCg powder.
2. Pull out 1cc of water using a syringe, and put it in the amp with HCG. The dissolution will happen instantly.
3. Put 4ml of water in one of the 5ml empty vials.
4. Take the syringe and then add the mixture of HCG solution in the 5ml vial.
5. Shake the whole mixture gently. This will yield to 5,000 IU of HCG.
6. Draw 1cc of the mixture, and inject in the desired site.
7. Refrigerate the remainder of the solution.

Other Factors to Consider
Keep in mind that proper discarding of the ampoule of solvent is crucial as it is manufactured for one-time use only. It is not advised to refrigerate the same item and re-use it a week later or any other time.
All in all, the most common side effects of HCG use include gynecomastia. Hence, the concurrent intake of Nolvadex with HCG will prevent this side effect, or at least minimize the desensitization of Leydig cells, while promoting the stimulation of the pituitary LH during a discontinued HCG usage. The desired effects last for approximately 30 days once mixed with bacteriostatic water, instead of any solvent. The mixed solution will last as long as proper sterilization and refrigeration is applied.