PeptideGuide 2013
With the launch of a peptide range immanent, now is the time to understand the differences and function of the main peptides we will be able to get our hands on.
Peptides are short polymers of amino-acids linked by peptide bonds. They have the same protein-peptide bonds as those in proteins, but are usually shorter in length. The shortest peptides are called di-peptides consisting of two amino acids joined by a single peptide bond. There can also be, tetrapipteds, pentapeptides, etc. Research Peptides have an amino end and a carboxyl end, unless they are cyclic peptides. A polypeptide is a single linear chain of amino acids bonded together by peptide bonds. Protein molecules consist of one or more polypeptides put together typically in a biologically functional way and sometimes have non-peptide groups attached. These groups are called prosthetic groups or co-factors.
Peptides, by definition must maintain certain characteristics. One of those being that the peptide chains must be short enough to be made synthetically from the constituent amino acids. Then they are considered to be called peptides rather than proteins. However, with the advent of better synthetic techniques, peptides as long as hundreds of amino acids can be made, including full proteins like uniquitin. Native chemical ligation has given access to even longer proteins, so this convention of definition seems to be outdated.
Another definition places an informal dividing line at approximately 50 amino acids in length (some people claim shorter lengths). This definition is somewhat arbitrary. Long peptides, such as the amyloid beta peptide linked to Alzheimer’s, can be considered proteins; and small proteins, such as insulin, can be considered peptides.
In simple terms and in a way all bodybuilders would understand – Synthetic Growth Hormone is a complete protein and 191 amino acid chain where as CJC1295 has a 30 amino acid peptide chain.
GHRP-6
Growth hormone releasing peptide-6 (GHRP6) is a growth hormone releasing hormone. GHRP 6 is a true hGH secretagogue. Which means it stimulates the body's own secretion of hGH after subcutaneous administration (carefully measured).
GHRP-2, GHRP-6, Ipamorelin and Hexarelin are replaceable ghrps sharing similar mechanisms of action. GHRP peptides for sale however have small differences and therefore different athletes have preferences (ie.] GHRP-6 up to 100mcg has no increase of cortisol and prolactin levels.
5000mcg per vial
Reconstitute - with 1ml or 2ml of water (but with the small measurements we suggest you use 2ml) depending on the brand used. GHRP-6 Dosage]100mcg to 300mcg as many as 5 times a day.
Usually between 3 to 5 times per day before meals.* Always take your last injection at bed time.
If you mix your GHRP6 5000mcg with 2ml of water then a 100mcg dose will measure 4 ticks on your insulin syringe.
Because of the frequency of injections it would be best to use the precise insulin syringes, the smaller the pin the better.
Tips]- GHRP2 and GHRP6 works best if coupled with CJC-1295 to get the most out of the peptides.
- Intramuscular and subcutaneous routes lead to different onset times but roughly similar peaks and declines.
- It can be used alone or in conjunction with Growth Hormone.
Post-injection]- Alternatively you can inject gh peptides at 1 to 1.5 hours after a meal.
- Do not combine GHRP-6 and GHRP-2 in a cycle. It has very similar effects with small differences and preferences from person to person.
Functions
Increases muscle mass and reduce body fat. Increases appetite but not as dramatically as GHRP-2. GHRP-6 keeps your endogenous (natural) GH production flowing. It also strengthens the joints, connective tissue and bone mass.
GHRP2
It is a growth hormone releasing hormone. GHRP-2 is a synthetic ghrelin analogue. Unlike ghrelin (that plays a large role in inducing hunger), GHRP-2 is not lipogenic and does not induce fat storage.
GHRP-2, GHRP-6, Hexarelin and Ipamorelin are replaceable research peptides in the ghrp dept having similar mechanisms of action as well as brief acting growth hormone results. GHRP Effects they do however have small differences and therefore different athletes have their preferences according to best suit the individuality of each lifestyle.
GHRP-2 has a medium increase of cortisol and prolactin levels and is therefore the best-selling GHRP2 for experts (many see value in ghrp-6 with the misconception that the higher # equates to value/results).
5000mcg per ghrp2 vial
Constitute - with 1ml or 2ml of water (but with the small measurements we suggest you use 2ml) depending on the brand you use. Ghrp-2 Dosage]100mcg to 300mcg 2 to 4 times daily.* Always take your last injection at bed time.
First time in the morning when you wake up on an empty stomach 15 minutes before eating.* Post workout directly after training 15 minutes before eating or having your protein drink. Before bedtime, 15 minutes before taking a pure protein. Do not take a protein carb mix and go to bed because that will make you fat.
If you mix your GHRP2 5000mcg with 2ml of water then a 100mcg dose will measure 4 ticks on your insulin syringe. Not 40 but the small 4 ticks. 200mcg will be 8 ticks if you use 2ml of water and so on.
Because of the frequency of injections it would be best to use the insulin syringes with a 8mm x 30 gauge (0,30mm) needle on. This is the smallest needle you can get.
Tips]- GHRP2 and GHRP6 works best if coupled with CJC-1295 to get the most out of the peptides purchased.
- Intramuscular and subcutaneous routes lead to different onset times but roughly similar peaks and declines.
- It can be used alone (GHRP advisably) or (both GHRP/GHRH) in conjunction with Growth Hormone (191aa GH).
Post-injection]- Alternatively you can inject it 1 to 1.5 hours after a meal.
- Do not combine GHRP-6 and GHRP-2 in a cycle. It has very similar effects with small differences and preferences from person to person.
Functions]Increases muscle mass and reduce body fat. Increases appetite dramatically. GHRP6 keeps your endogenous (natural) GH production flowing.
CJC-1295
CJC1295 has a very long half-life and therefore it has no dietary restrictions or specific times that you. Because of its long half life it has long term benefits on your body’s basal GH levels.
CJC1295 is a 30 amino acid peptide hormone where synthetic growth hormone contains a 191 amino acid chain. It attaches itself to the albumim receptor and this increases its half life oppose to the normal growth hormone releasing hormones.
2000mcg per vial
Reconstitute - with 1ml of water depending on the brand you use. CJC-1295 Dosage]1000mcg (1mg) twice a week or 2000mcg (2mg) once a week.
Dose per injection]
Injections per vial]Amount to Inject: If you have used 1ml of water for mixing then a 2mg dosage = 1ml (or 100 units on Insulin Syringe). If you want to inject 1mg twice a week and you have used 1ml of water then a 1mg dosage = 0.5ml (or 50 units).
Because of the frequency of injections it would be best to use the insulin syringes with a 8mm x 30 gauge (0,30mm) needle on. This is the smallest needle you can get.
Tips]Because of its long acting properties this product works best in conjunction with short acting growth hormone releasing hormones like GHRP-2 and GHRP-6 to take advantage of the short-term GH pulse created after a CJC1295 injection.
Intramuscular and subcutaneous routes lead to different onset times but roughly similar peaks and declines.
Functions]This product was initially developed for AIDS patients that were obese. It increases muscle mass and decrease body fat.* Increase lean muscle mass. Decrease body fat percentage. Increase growth hormone secretion of the pituitary gland.
Hexarelin
Hexarelin is the strongest of the GHRP peptides. It has a potent ability to stimulate growth hormone secretion. It has even reported to be able to reduce neonatal brain injuries in newborn babies.
GHRP-2, GHRP-6 and Hexarelin are replaceable peptides for research and have similar mechanism of action. Hexarelin has a high increase of cortisol and prolactin levels. Cheap hex is often 2000mcg per vial.
Reconstitute - with 1ml or 2ml of water (but with the small measurements we suggest you use 2ml) depending on the brand/size.
Hexarelin Dosage]25mcg to 50mcg - 1 to 6 times a day. Cycles last for as long as three months. The time between injections should be 3-4 hours. Always take your last injection at bed time.
If you constitute your 2000mcg of Hexarelin with 2ml of water 50mcg of Hexarelan will amount to 5 ticks on the insulin syringe. 25mcg will then be 2.5 ticks on the syringe. Not 50 marks on the syringe but the small 5 ticks.
-
Because of the frequency of injections it would be best to use the insulin syringes with a 8mm x 30 gauge (0,30mm) needle on. This is the smallest needle you can get.
Tips]- The main difference of Hexarelin from GHRP-6 is that Hexarelin does not promote appetite, because it does not increase the level of ghrelin in the body.
- The fact that Hexarelin it does not increase the appetite means it is better for athletes busy dieting who wants to suppress their appetite where GHRP-6 and GHRP-2 (to a extent) is better for athletes wanting to bulk and need the increase in appetite.
- Post-injection]- Alternatively you can inject it 1 to 1.5 hours after a meal.
Functions]- The main effects of Hexarelin include increase of strength, growth of new muscle fibers, improving of vessels state, reduction of fat mass.
- Medicinally, Hexarelin can be used to treat GH deficiency induced diseases.
- This drug proved to be a great healer of wounds and can be administered as a multipurpose anabolic and with the purpose to stimulate endogenous GH secretion inhibited with the use of synthetic GH. In other words where synthetic growth does not increase the body’s ability to manufacture more GH the Hexarelin does.
Sermorelin
Sermorelin is used for its anti aging properties. It is one of the weakest peptides on the market. This is a grf 1-29 amino acid chain peptide where synthetic growth hormone contains a 191 amino acid chain. Sometimes Sermorelin is referred to as GRF 1_29. It is also a growth hormone releasing hormone (GHRH) acting for a very brief window of opportunity.
2000mcg per vial
Reconstitute - with 1ml of bac water. Sermorelin Dosage]300mcg to 600mcg per day. This is similar to taking 1IU to 2IU of growth hormone per day. (1IU = 333mcg).
Similar to synthetic growth hormone you take Sermorelin before you go to bed for fat burning and anti aging properties. Alternatively you can take it when you wake up in the morning and this will have more of a bulking effect.
If you constitute your 2000mcg of Sermoralin with 1ml of water 300mcg will amount to 15 ticks on the insulin syringe. 600mcg will then be 30 ticks on the syringe.
Tips]- Sermorelin is the same as CJC-1295 but without the long acting properties.
- Very similar to growth hormone it takes a couple of weeks to kick in.
- Many charactaristics of Sermorelin is similar to that of synthetic growth hormone.
- Sermorelin is basically a natural alternative to synthetic growth hormone and gets administered the same way.
Functions]Sermorelin (GRF 1-29) is a natural alternative to growth hormone and was found to contain the most evident 29 amino acids that stimulates the pituitary gland to increase growth hormone levels. This compound is mainly used for the rejuvenation of cells and anti aging purposes. Sermorelin reduces body-fat and increases lean muscle the same way growth hormone does.
As per normal synthetic growth hormone Sermorelin (GRF1-29) has the following functions]- Increased energy & strength
- Increases natural production of Human Growth Hormone HGH
- Improves Physical and Mental Performance
- Improves Immune Function
- Increases IGF-1
- Improved wound healing
- Improved heart function
- Increased calcium retention and bone density
- Improves sleep quality and combats insomnia
Wow. I was amazed as to how diligent you are in posting relevant information in this forum! I see you starting informational thread all the time. Just keep in doing that to encourage more users to participate in our discussions here. The more is the merrier.
From the list of peptides you have listed above, I can only identify GHRP-2 and GHRP-6. Well, that is not a surprise as I am only a newbie. However, thank you for introducing me to hexarelin, GRF-129, sermorelin and the likes!
Wow! This is such an informational thread. This is where should newbies go when trying to choose which peptides to use. This will give them an idea on what to expect from each peptides.
Reply With Quote
