Had 1mg of Bremelanotide (PT-141) left over from my last experiment with the stuff. Figured it wouldn't do anything, but it was just lying around anyway, so I tried it intranasally to see if Palatin’s in-development delivery system could be recreated. It works folks. Intranasally as well as sub-cutaneously — it works. Something that I think I didn’t adequately describe in previous entries is the degree to which this drug does NOT act acutely. It takes hours and hours (after the initial flushing effect) to experience its pro-sexual effects. Perhaps 3-4 hours after dosing, I fell asleep, having not yet experienced the pro-sexual effects. But this morning I would have broke the rigiscan — that strange contraption they use in clinical trials to measure the effects of “male research” drugs — had I been subjected to it. Another thing to emphasize is the utter randomness of the erections. Viagra works very simply]
IS BREMELANOTIDE (PT-141) THE ANSWER?
That said, a drug I have currently been messing around with called Bremelanotide (previously called PT-141) has been touted by some as the female Viagra. In rats, at least, Bremelanotide increases “female sexual solicitation behavior,” an exciting (so to speak) finding to say the least. Then again, if rat behavior perfectly correlated with that of humanity, obesity would be a thing of the past]
So, does Bremelanotide work? Is it the female viagra, or is it bunk junk?
Alcibiades’ bold prediction is that this stuff will work — not for every female — but that it will exert a pro-sexual effect on a considerable subset of the female population. I base this on personal experience, though the careful reader will note that I have been endowed with the Instrument of Adam, not Plato’s Cave.
My own personal experience with the drug was suggestive. And the thing about Bremelanotide is that its effects are very difficult to mistake for Lady Placebo. Acutely, it flushes the face like — well, a lot like the head of an engorged…tomato. Quite a while after the initial dosing after, often 3-6 hours later, you become aware of a “pressure” in the loins. It’s something like an internal tickle down there. And, behaviorially, you just end up grabbing your ding dong more. You just sort of need to. It’s like a compulsion or something.
Now unfortunately, not everyone is as enthusiastic about “introspective research” of unapproved pharmaceuticals as I, so I cannot confirm that these effects are the same in women. Still, the more-than-just-blood-flow effects I experienced lead me to believe that this stuff may well do something for the fairer sex.
Bremelanotide, if approved, will not be available for another few years. For the FDA, like a hot date, likes to make us wait. If in the meantime the anticipation is killing you (and you are a post-menopausal women), you might try the testosterone patch, which seems to be useful for some — though the potential for masculinizing effects scare a lot of folks off. (Probably rightly.) Perhaps the most important thing to do if you are a female suffering from sexual dysfunction is to make sure you make sure you aren’t already on something that could be affecting your libido]
And that is all I have to say about that.
Brem is for Real
By Alcibiades
First off, I am sick of typing out Bremelanotide (PT-141). From now on it’s Bremelanotide. Scratch that, it’s “Brem.”
Injecting Brem 4mg sub-q was an interesting experience. First off, I’m evidently pretty rusty from my days of slamming steroids on a daily basis. In those days, when I was sticking girthy 23? gauge needles 2 inches into my ass cheek, I would have laughed at my present-self experiencing a profound sympathetic response to the act of slipping a diminutive insulin needle under the skin.
(Note that I wasn’t about to waste a prohibitively expensive compound by going the intranasal route. As alluring as it is to have libido in an easy-to-inhale form. Great marketing by the way, Palatin.)
So I constituted the peptide (put the powder into bacteriostatic water), prepared a 4mg-in-1ml dose, and injected it into the subcutaneous fat layer that remains atop my stomach despite prodigious cardio on my part!
20 minutes later, my face turned way-the-fuck red. Mars-rock red. Uneven blemishes and former acne became very visible, lit up seemingly from within like Christmas lights. I definitely was experiencing a headache. All in all, I didn’t feel so good.
No spontaneous erections to speak of. No increased desire for my fellow classmates, or, for that matter, the scantily- or not-so-clad women I “tested” myself with on the internet.
When the flushing and headache diminished perhaps an hour later, I was ready to dismiss this drug as more drug company hype. Yeah, blood flow was effected at some level, but a “designer aphrodisiac” Brem was not.
Approximately 3 hours after dosing, I found out how wrong my initial assessment was.
The most peculiar thing]
The effects of Brem were immensely prominent until I went to sleep (6 hours later?) hours following the inject. Additionally, random erections, uncomfortable jeans-hugging stiffies, and especially that ever-present “need to satiate” were very noticeable for the next few days. (I suspect the duration of effect is due to large amount used and to the “slow trickle” of active compound from fat stores into the blood stream, though this is just a hypothesis.) Pronounced yawning as well, which jives with Brem’s purported action on the hypothalamus, and its effects on the old pogo stick.
Alcibiades’ Bottom Line]
Banging Bremelanotide
By Alcibiades
Bremelanotide (a.k.a. PT-141) most definitely works! The flush reminds me of a woman’s “sex flush.” I even took pics of myself to document the remarkable deep red (tomato-like) color you turn — it is not normal! (No, I’m NOT showing you!) The psycho-physiological effects are distinctively reminiscent of puberty. There is a strange tightening in my pelvic region that I perceive the need to satiate.
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