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  1. #1 7th March 2010 
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    Bremelanotide (PT-141) Guide

    Peptide-Guide Bremelanotide PT-141
    [b]Bremelanotide PT-141 Dosing]
    Light]Common:* 1mg
    Large]
    Bremelanotide (PT-141)
    was developed from Melanotan 2 (MT-II), which was tested as a sunless tanning agent.* PT-141 is a metabolite of MT-II that lacks the C-terminal amide function-stripping away tanning properties.*


    [b]Treatment]* PT-141 is the only synthetic aphrodisiac.* Studies have shown Bremelanotide to be effective in treating sexual dysfunction in both men (erectile dysfunction or impotence) and women (sexual arousal disorder).* Unlike Viagra and other related medications (PDE5s), PT-141 does not act upon the vascular system, but directly through the nervous system (hypothalamus) to increase desire.* Viagra, Cials and Levitra are not considered aphrodisiacs as they do not have any direct effect on the libido.* However, treatment with PDE5 inhibitors and PT-141 are known to have a synergistic effect.

    Bremelanotide is a melanocortin peptide hormone.* PT-141 binds to the melanocortin 4 receptor (MC4R) in particular.* Nine out of ten volunteers experienced sexual arousal in trials.* The desire is one of the more sought after effects unique to the peptide.

    Reconstitute and use PT-141 for Research via youtube
    [b]Mixing] Bacteriostatic water is used for reconstitution.
    Example-* 1ml(cc) bacteriostatic water per 10mg PT-141 vial equates to a 1mg dose approximately each 10 units on a U100 insulin syringe.
    Example-* 1ml(cc) bacteriostatic water per 2mg PT-141 vial equates to a 1mg dose approximately every 50 units on a U100 insulin syringe.

    Recommended strategy for mixing and dosing would be to reconstitute with the volume that yields a .1ml injection.

    Example-* 1ml(cc) bacteriostatic water per 10mg PT-141 vial equates to a 1mg dose approximately each 10 units on a U100 insulin syringe.
    Example-* .2ml(cc) bacteriostatic water per 2mg PT-141 vial equates to a 1mg dose approximately every 10 units on a U100 insulin syringe.



    Bremelanotide PT-141 Peptide]
    [b]Window of Opportunity]
    Although injected (subcutaneously), Bremelanotide has a unique window of opportunity lasting six to 72 hours.* In lab trials, female rats exposed to PT-141 immediately began "flirting" with male rats for sex. Postures and movements left no doubt in the male rats minds that they were in the mood.

    [b]Dosing] Read as much as possible to gain clarity and align expectations.* Gradually dosing increases likelihood for success without sides.* A test dose of .25-.5mg on the first attempt is recommended.* 1mg, give or take a quarter, is the efficacious dose which yields the most hero stories reported by users.

    Women who took part in trials said that they felt a "tingling and a throbbing" along with "a strong desire to have sex."* An initial flush occurs post injection, followed by nausea which is dose dependent.* For most, effects generally do not take place until a couple hours post injection, peaking around the four hour mark.*

    Men said PT-141 made them feel "younger and more energetic" as well as sexually interested and aroused. "You're ready to take your pants off and go," said user "a drug that makes you not only able to but eager to."
  2. #2 21st August 2010 
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    Re: Bremelanotide (PT-141) Guide

    Do you mean I have to inject yourself with this?
  3. #3 21st August 2010 
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    Re: Bremelanotide (PT-141) Guide

    Do you mean I have to inject myself with this?* I am going to drink it tomorrow and will let y'all know if it worked for me.* I realize from reading more of the blog responses that orally ingesting it has been shown to only work with a third of the guys who tried it like that.* I will write down if it worked, how long it took to work, and how long it lasted. I take meds for slow metabolism and I exercise.
  4. #4 21st August 2010 
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    Re: Bremelanotide (PT-141) Guide

    "
    Do you mean I have to inject yourself with this?
    "

    Correct, subcutaneous administration is the only way at this time (unfortunately)
  5. #5 22nd December 2010 
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    Re: Bremelanotide (PT-141) Guide

    "
    "
    Do you mean I have to inject yourself with this?
    "

    Correct, subcutaneous administration is the only way at this time (unfortunately)
    "

    It is either 20mg nasally or 1mg subq
    $80 per dose or $5

    Most choose subq for PT-141 trial